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Emedastine (em-e-DAS-teen) ophthalmic solution is used to treat symptoms of the eye caused by allergic conjunctivitis. It works by preventing the effects of a substance called histamine, which is produced in certain cells in your eyes and which causes the allergic reaction. In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For emedastine, the following should be considered: Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to emedastine. Also tell your health care professional if you are allergic to any other substances, such as preservatives.

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Pregnancy - Emedastine has not been studied in pregnant women. However, studies in animals have shown that emedastine, when given in very high doses to some types of animals, causes birth defects. Before using this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant. Breast-feeding - It is not known whether enough ophthalmic emedastine is absorbed by the body to pass into breast milk. However, be sure you have discussed the risks and benefits of the medicine with your doctor. Children - Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of ophthalmic emedastine in children younger than 3 years of age with use in other age groups. Older adults - Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of ophthalmic emedastine in the elderly with use in other age groups.

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Do not wear contact lenses if your eyes are red. If your eyes are not red, contact lenses should be removed before you use this medicine. Also, you should wait at least 10 minutes after using this medicine before putting the contact lenses back in. First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed for 1 to 2 minutes to allow the medicine to be absorbed by the eye.If you think you did not get the drop of medicine into your eye properly, use another drop.To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed. The dose of emedastine will be different for different patients. Follow your doctor's orders or the directions on the label.

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Darifenacin (dar-i-FEN-a-cin) is used to treat bladder problems such as frequent need to urinate or loss of control of urinary function. In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For darifenacin, the following should be considered: Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to darifenacin. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes. Pregnancy - Darifenacin has not been studied in pregnant women. However, studies in animals have shown that darifenacin may cause unwanted effects in the fetus. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.

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Breast-feeding - It is not known whether darifenacin passes into breast milk. However, darifenacin does pass into the milk of animals. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor. Children - Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of darifenacin in children with use in other age groups. Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.