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Hepatitis B vaccine recombinant is made without any human blood or blood products or any other substances of human origin and cannot give you the hepatitis B virus (HBV) or the human immunodeficiency virus (HIV).

HBV infection is a major cause of serious liver diseases, such as virus hepatitis and cirrhosis, and a type of liver cancer called primary hepatocellular carcinoma.

Persons with blood clotting disorders who receive transfusions of clotting-factor concentrates.

Household and sexual contacts of HBV carriers.

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to this vaccine or to the hepatitis B vaccine made from human plasma. Also tell your health care professional if you are allergic to any other substances, such as foods (especially yeast). The vaccine is made by using yeast; persons allergic to yeast may also be allergic to the vaccine.

Pregnancy - Studies on effects in pregnancy have not been done in either humans or animals. However, the vaccine is not expected to cause problems during pregnancy.

Hepatitis B vaccine is very effective when administered to adolescents and young adults. It is recommended that all adolescents who have not previously received three doses of hepatitis B vaccine should start or complete the vaccine series at 11 to 12 years of age. Hepatitis B vaccine has not been shown to cause different side effects or problems in adolescents and young adults than it does in other age groups.